PATHS-UP Engineering Research Center (ERC) was funded by the National Science Foundation (NSF) in 2017. PATHS-UP mission is 1) to engineer transformative, robust, and affordable, technologies and systems to improve healthcare access, enhance the quality of service and life, and reduce the cost of healthcare in underserved populations. The PATHS-UP ERC team is led by Texas A&M University, with partners from the University of California at Los Angeles, Rice University, and Florida International University.